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In clinical trials, Mounjaros active ingredient, tirzepatide, helped people lose 22.5% on average, while semaglutide (Ozempic and Wegovys active ingredient) helped people lose around 21% of their starting weight

Exercise-induced brachial artery vasodilation: effects of antioxidants and exercise training in elderly men

While weight loss in the semaglutide group is consistent with the typical effects of these meds, the level of pain reduction surprised the researchers

Glycaemic effect is modest

The 40% contamination rate found in compounded semaglutide products applies broadly to the unregulated peptide market

So then talk us through how did they get into more of the mainstream