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Autologous multi-tissue OoC platforms, by integrating multiple primary or stem cellderived cell types from the same individual within interconnected microphysiological compartments are the new frontier, since they offer a powerful approach to faithfully replicate a specific pathology including in the very same model both inter-organ interactions and patient-specific physiology

Bile acids alter male fertility through G-protein-coupled bile acid receptor 1 signaling pathways in mice

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We advise clients to consider the natural role of glutathione in detoxification and immune function

Vital signs including blood pressure, heart rate, and body temperature remained stable

APE1 was also one of the many non-regulatory proteins involved in cancer survival signaling pathways, and could be used as a therapeutic target in the treatment of multiple types of tumor cells [24]