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doi: 10.4103/ijmr.IJMR_1937_17 2 GanieMAChowdhurySMalhotraNSahayRBhattacharyaPKAgrawalSet al

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Diacylglycerol and ceramide accumulation Consistent with the above studies, elevated plasma fatty acid concentrations can result in increased intracellular diacylglycerol (DAG) levels, leading to the activation of protein kinase C isoform (PKC-) and PKC- isoforms in skeletal muscles and liver respectively