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In summary, adhering to the teams prior isolation technique for acquiring BMSCs(Wang et al., 2018), the isolated BMSCs were cultivated in a complete medium comprising 1% streptomycin/penicillin, DMEM, and 10% fetal bovine serum (FBS, Gibco, United States)

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GLP-1 receptor agonists (GLP-1RAs), designed to mimic native GLP-1 while resisting degradation by dipeptidyl peptidase-4 (DPP-4), have become foundational in T2DM pharmacotherapy