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Optimal preparation methods for automated matrix-assisted laser desorption/ionization time-of-flight mass spectrometry profiling of low molecular weight proteins and peptides

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These peptides fold, carry hydrophobic acyl chains, and present several interaction points to the stationary phase at once, which is why their retention behaves so differently from a small molecule

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While these combinations are interesting, they make it difficult to assess PTD-DBM effects specifically

doi: 10.7326/0003-4819-141-11-200412070-00035 64