Discussion In this single-center, retrospective, real-world cohort study, escalating the OW semaglutide dose from 0.5 to 1.0 mg was associated with additional reductions in the HbA1c level and body weight at 24 weeks
Patients with pre-existing diabetic retinopathy should have regular ophthalmological assessments, as rapid improvement in glucose control can temporarily worsen retinopathy
Responses were observed regardless of RET pathogenic variant status
Administration Injectable GLP-1 medications: Self-administered subcutaneous injection Small needle, minimal discomfort for most Common injection sites: abdomen, thigh, upper arm Rotate sites to prevent tissue irritation Most are once-weekly (semaglutide, tirzepatide, dulaglutide) Oral semaglutide (Rybelsus): Must be taken on empty stomach No more than 4 oz water Wait 30 minutes before eating or taking other medications Daily dosing Long-Term Considerations Understanding the long-term picture helps with treatment planning
Thats why telehealth providers such as Noom Med, which is an offshoot of popular weight-loss platform Noom, prescribe a wide range of GLP-1s
The Latin America GLP-1 agonists market size for pens still dwarfs tablets, but oral formats will increasingly attract first-line therapy seekers who dislike injections