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Protein bands were visualized using Immobilon Western Chemiluminescent HRP Substrate (Merck Millipore, Billerica, MA, USA) and a ChemiDoc MP Imaging System with Image Lab Touch Software Version 1.0 (Bio-Rad Laboratories, Hercules, CA, USA)

| Placebo | 2.5 | 25 | 10 | 3 | 1 | 2

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Methods Materials Diamide, dithiothreitol (DTT), ethylenediaminetetraacetic acid (EDTA), GSH, GSSG, and yeast GR were from Sigma-Aldrich, l-cysteine was from Carl Roth, isopropyl--d-1-thiogalactopyranoside was from Serva, methyl ether poly(ethylene glycol) 24 maleimide (mmPEG) was from Iris Biotech, and NADPH was from Gerbu