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Avoid self-medicating with unlicensed or unverified products purchased online, which carry significant and unpredictable health risks

Still, major trials on two GLP-1 drugs (tirzepatide and semaglutide) offer some information about the impact of these medications on muscle loss, according to a 2025 analysis in Obesity Reviews

GLP-1 receptors arent just found in the pancreas and brain

Avoid repeated temperature cycling

Most people lose weight but accidentally lose muscle

Some analysts said the new results showed that both drugs which Roche acquired through its nearly $3 billion acquisition of Carmot Therapeutics in December caused a higher rate of side effects than expected