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MEDI0382, a GLP-1/glucagon receptor dual agonist, meets safety and tolerability endpoints in a single-dose, healthy-subject, randomized, phase 1 study

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Cardiovascular Risk Reduction: Clinical studies have shown that semaglutide can reduce the risk of major cardiovascular events, such as heart attacks and strokes, in adults with type 2 diabetes and pre-existing cardiovascular disease

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There is also interest in investigating the drugs impact on the gut microbiome and its interaction with dietary interventions, given the growing recognition of diet-microbiome interactions in IBS pathophysiology

Availability of data and materials All data generated or analysed during this study are included in this published article