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Short interfering RNA-mediated silencing of glutaredoxin 2 increases the sensitivity of HeLa cells toward doxorubicin and phenylarsine oxide

In INS-1E cells, silencing of the malate/aspartate transporter Aralar1 in the mitochondrial inner membrane that is necessary for the malate/aspartate shuttle partly impairs GSIS [27], further suggesting a role for the malate/aspartate shuttle in GSIS

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Gomez-Cabrera M, Ristow M, Via J

doi: 10.1371/journal.pone.0097861 445 LavasaniSDzhambazovBNouriMFakFBuskeSMolinGet al

In addition, we describe recent developments in preclinical models of BM and consider their relevance to investigating radiation response