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In macrophages, silence of the SLC7A11 gene promotes iron overload-induced ferroptosis, suggesting that the TGF signaling pathway is crucial for regulating macrophage ferroptosis (21, 80, 81)

(ii) changes in energetic metabolites, with upregulation of methylmalonate and malate, and a decrease in glucose

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Vitamin C pharmacokinetics: implications for Oral and intravenous use

Most available research covers short-term use up to several months, with no major safety signals identified