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All tissues were collected from females (aged 50-100 days old) in estrous, verified by cytological smears, to ensure that any differences in gene expression were not due to the cyclical changes in hormone levels

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3.1.1.4 m 6 A modification N6-methyladenosine (m 6 A) is the most prevalent internal modification of mRNA in eukaryotes, influencing various aspects of RNA metabolism, including stability, splicing, translation, and localization