239,240 In summary, GLP-1 lowers blood glucose levels and inhibits glucagon secretion through direct action on -cells, promotion of insulin secretion, and regulation of gastrointestinal activity
Clinicians should encourage nutrient-dense food choices, emphasizing lean proteins (1.0-1.2 g/kg body weight daily during active weight loss to preserve lean mass), vegetables, fruits, whole grains, and healthy fats
123 PEG-loxenatide is used for blood glucose control in adult patients with T2DM
Back Turton, MD, O'Shea, D, Gunn, et al (4 Jan 1996) 'A role for glucagon-like peptide-1 in the central regulation of feeding', Nature , 379, 69-72
M., Luis, P
To their credit, public companies distributing compounded GLP-1 drugs have acknowledged this risk