Methodology Protocol registration This systematic review and meta-analysis followed the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) statement 11 and the Cochrane Handbook for Systematic Reviews and Meta-Analyses guidelines
Where These Numbers Come From The retatrutide + cagrilintide combination has no published clinical trial as of May 2026
In Phase 2 trials, female participants actually achieved slightly higher average weight loss than men at 25.3% versus 22.8% over 48 weeks
As adoption accelerates in the UK and around the world, these medicines are reshaping how people eat, shop, and engage with brands, creating both disruption and opportunity across food, retail, and health ecosystems
Biochimie 133 , 95102 (2017)
Perfectly round numbers suggest the result was decided before the test was run