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Having smaller meals that are frequent, keeping hydrated, and opting for blander foods when you first start the medication can help reduce stomach upset

Published studies with metformin use during pregnancy have not reported a clear association with metformin and major birth defect or miscarriage risk (see Data )

If your bottle delivers 0.12 mL per actuation and you calculate for 0.1 mL, every dose across your entire study is running 20% higher than your protocol intends

Level 2 evidence corresponds to cohort studies or systematic reviews of cohort studies