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Pro-inflammatory cytokines disrupt neurotransmitter metabolism through mechanisms such as inhibited tryptophan conversion to serotonin while driving microglial activation, thereby amplifying neuroinflammation (271)

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Additionally, patients in the HGSH group (high GSH intake, 16 days) exhibited an elevated recurrence rate compared to that in the LGSH group (low GSH intake, 0.05) (Supplementary Table 4)

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