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Moreover, the treatment of naltrexone together with either varenicline or bupropion reduces alcohol consumption in rats (Zhou et al., 2019

One year after discontinuation, patients treated for obesity had gained 0.5 % of their baseline weight, whereas those treated for T2DM had lost a further 1.3 %

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If you're managing a condition with elevated oxidative stress, monitor for symptom return around week 23 and discuss maintenance dosing or alternative antioxidant support with your prescriber