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miRNAs are small (2023-nucleotides), endogenous, single-stranded noncoding RNAs that regulate gene expression by pairing to sequence-specific binding sites in mRNAs to direct post-transcriptional repression and consequent inhibition of protein translation or degradation of the mRNA targets [179,180,181]

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Trials differ in whether participants have diabetes, in baseline body weight, in age distribution and in the conditions that excluded people from enrolling