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Modern IV equipment with air-detection sensors has made this event extremely rare, and fully priming IV tubing before use is the main preventive step

Indeed a review article concluded that in prospective trials, therapeutic doses of paracetamol do not cause toxicity, and notes that only in retrospective studies does therapeutic toxicity occur and this is likely due to the biases inherent in retrospective analysis [2, 6, 7]

January 2024

References 1.Southorn PA, Powis G

Unlike nuts that grow individually, the seeds of the Brazil nut tree grow in a pod that resembles a coconut

This work was supported by the National Natural Science Foundation of China (grant no