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Cost-effectiveness studies conducted in the UK, Portugal, Canada, and the United States consistently concluded that semaglutide is cost-effective relative to lifestyle management and other pharmacotherapies, including liraglutide (2127)

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Guidance on injection technique for retatrutide is extrapolated from established subcutaneous injectable therapies such as semaglutide (Wegovy/Ozempic) and tirzepatide (Mounjaro), which share a similar administration route