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Description

Connective tissue support pathways

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TB-500 binds monomeric G-actin through the central LKKTETQ motif, sequestering actin monomers and modulating the cytoplasmic pool available for filament elongation in cell-based assays

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Starting at the lower end allows assessment of individual tolerance before increasing if needed

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This process helps the body utilize fat for energy and supports normal metabolic functions

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10.1038/s41467-020-18249-3 [DOI] [PMC free article] [PubMed] [Google Scholar] Zobel, E

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