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The dose-response curve explained At the 1mg level, participants lost 8.7% of body weight over 48 weeks

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These results support the remarkable potential of this novel molecule for people living with type 2 diabetes, with up to 2% A1C improvement and nearly 17% weight loss in 40 weeks of treatment." The most common side effects were nausea, diarrhoea and vomiting, mainly during the early weeks of treatment, consistent with other drugs in the class

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Authorship note: MS and MMH contributed equally to this work