The study in Molecular Nutrition and Food Research is one of the most relevant pieces of preclinical evidence for niacinamide use in metabolic contexts
Specific situations warrant urgent professional dietary consultation: Unintentional excessive weight loss losing more than 1 kg weekly consistently, or experiencing rapid weight loss that feels uncontrolled Inability to meet minimum calorie requirements due to severe appetite suppression, nausea, or other side effects Signs of nutritional deficiency , including unusual fatigue, weakness, hair loss, brittle nails, frequent infections, or poor wound healing Pre-existing eating disorders or disordered eating patterns, as GLP-1 medications may complicate these conditions Complex medical conditions such as chronic kidney disease, liver disease, or malabsorption disorders requiring specialised dietary management Pregnancy or breastfeeding GLP-1 medications should not be used during pregnancy
2014 Feb;13(1):8-12 Aquilano K, Baldelli S, Ciriolo MR
Its best to consult with your dermatologist for individualised recommendations
Third, heterogeneity in study designs, primary endpoints, and biomarker assessments limits direct comparability and generalizability
doi: 10.1093/ijnp/pyv021