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Lastly, cysteine amides, as proxies for protein cysteines, also undergo lactoylation by MG and LGSH, suggesting the existence of two additional pathways for nonenzymatic lactoylation of proteins

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a bridging adaptor protein, apoptosis-associated speck-like protein containing a CARD (ASC)

Also, because of its synergistic effect on two receptors, it has a greater effect on weight loss and blood sugar control than GLP-1s alone

Secondary outcomes included the pharmacokinetic profile of PG-102, assessed using serum concentrationtime data and non-compartmental analyses, with exploratory pharmacodynamic and biomarker endpoints

Cell Stem Cell 11 (5), 596606