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Alcohol-associated liver disease mortality increased from 2017 to 2020 and accelerated during the COVID-19 pandemic

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69 Pegozafermin, a long-acting glycopegylated FGF21 analog, demonstrated improvement in liver fibrosis in MASH as shown in a 24-week phase 2B clinical trial (NCT04929483)

262 In summary, Met restriction (MR) can alleviate diabetes by interfering with glucose homeostasis, increasing insulin sensitivity and inflammatory response

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