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Hildreth, III , Sharma Sudarshana M., Pitarresi Jason R., Han Lu, et al

The present review adopts a TME phenotype-informed design logic to examine how recurrent structural and functional features of solid tumors shape drug delivery, therapeutic response and translational feasibility

At 6 weeks post-TAC surgery, echocardiography analyses of these mice revealed that TAC-operated animals exhibited significant reductions in EF and FS relative to sham control mice, whereas IVSd, LVIDd and LVIDs were increased, while PQQ treatment partially reversed this TAC-induced cardiac dysfunction (Figures 1BE)

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