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(Reporting by Sriparna Roy, Sneha S K in Bengaluru, Amina Niasse in New York

Robust, randomised, placebo-controlled human trials are essentially absent for both peptides

The guidelines state, However, pernicious anaemia in its true sense (that is, life-threatening anaemia) is now extremely rare because of developments in testing and treatment for, and greater awareness of, vitamin B 12 deficiency . In one sense, this statement is correct: the term pernicious anaemia, when taken literally, implies a severe, life-threatening form of anaemia, which is uncommon in modern practice due to improvements in testing and treatment, such severe manifestations are typically prevented, as the condition is more likely to be diagnosed earlier or treated with B 12

The production of myelin, the protective covering that envelops nerve fibers, is aided by vitamin B12

And the doctor who prescribed it would refute the lack of data, saying the absence of evidence is not evidence of absence, and that his patients are deriving substantial benefit without side effects

Unlike sterile water or saline, bacteriostatic water allows repeated withdrawals within 28 days, but should never be injected alone