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This work was supported by the National Research Foundation, funded by the Korean government (NRF-2020R1A3B2078617 to J.B.K.)
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NNMT silencing in adipose tissue reduced weight gain and improved glucose tolerance in high-fat diet models. Hong et al., Nature Medicine Improves Insulin Sensitivity Through its effects on NAD and adipose remodeling, 5-Amino-1MQ has been shown to improve glucose uptake and reduce insulin resistance, which is key for both fat loss and long-term metabolic health
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