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HUVECs (310 4 cells per well) were seeded in top chambers with DMSO or various doses of BPC-157 (1 g/mL, 5 g/mL, and 10 g/mL) in 500 mL RPMI 1640 with 0.5% FBS

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This relationship supports the hypothesis that much of tirzepatide's anti-inflammatory benefit may be mediated through weight loss rather than direct receptor-mediated anti-inflammatory signaling, though controlled studies specifically addressing this question are limited

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