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The effectiveness of tirzepatide for treating obesity is being evaluated in the SURMOUNT series of phase 3 RCTs, which, for the first time, demonstrated average weight reductions exceeding 20% with pharmacotherapy [23]

Accessed 28 Jul 2022 Lu J, Ma X, Zhou J et al (2018) Association of time in range, as assessed by continuous glucose monitoring, with diabetic retinopathy in type 2 diabetes

S-type analogs, such as semaglutide , have fatty acid side chains that bind albumin, extending activity

Key Features: GLP-1 R (50mg) activates the GLP-1 receptor , promoting insulin secretion in a glucose-dependent manner , which aids in regulating postprandial blood sugar levels and improving overall glucose metabolism

Adhikari U, Gad H, Chatterjee D, Malhotra C, Bhadada SK, Malik RA, et al

doi: 10.1111/dom.12085 [DOI] [PubMed] [Google Scholar] 60.Ribeiro-Silva JC, Tavares CAM, Girardi ACC