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The receptor is a class B G-protein-coupled receptor that signals mainly through cyclic AMP, and it is expressed far beyond the pancreas, in the brain, gut, vasculature, heart, and kidney

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As a result of their nutritional features, they can have a favorable effect on cell quality

Doi:10.1007/s13555-017-0194-1

Nutr 13(3) Mokadem M et al (2014) Effects of Roux-en-Y gastric bypass on energy and glucose homeostasis are preserved in two mouse models of functional glucagon-like peptide-1 deficiency