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GLP-1 agonists like Wegovy and Zepbound can lead to significant weight loss

In clinical trial settings, retatrutide is administered as a subcutaneous injection meaning it is injected into the fatty tissue just beneath the skin, rather than into a muscle or vein

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In another study, Ehmt2 mutant mice were used for the glucocorticoid-induced insulin resistance model, treated with Dex at a dose of 2 mg/kg body weight for 2 weeks