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In the OASIS 4 trial, adults taking Wegovy pill's 25mg dose lost an average of 17% of their body weight over 64 weeks, with early responders (over 10% lost by week 16) reaching 22% on average by the end

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(PubMed) Gunabalasingam S, De Almeida Lima Slizys D, Quotah O, et al

Stomach Issues ( source ) Ibuprofen is known to irritate the stomach lining, which can lead to ulcers, inflammation, and even bleeding in the digestive tract