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IV administration may cause rare allergic reactions

The 1.0 mg to 1.7 mg and 1.7 mg to 2.4 mg transitions are smaller relative increases, but cumulative GI adaptation means they usually feel less dramatic than earlier escalations

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It mimics ghrelin by binding to the ghrelin receptor (GHS-R1a) on the pituitary, which triggers the release of GH without significantly affecting other hormones such as cortisol or prolactin