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For instance, exendin-4 has been shown to ameliorate the high glucose-induced fibronectin (FN) and type I collagen (Col1) expression in tubular epithelial cells by inhibiting the secretion of miR-192, an microRNA (miRNA) that is regulated by p53 and plays a role in renal fibrosis (Yin et al., 2018)

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Eli Lillys retatrutide, which is in clinical trials, may help users shed up to 24% of their body weight after 48 weeks

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Data analysed by one-way ANOVA, multiple comparison, Bonferroni post hoc test ( e , f , k and l ) and two-way repeated measures ANOVA to assess main effects of treatment ( b , d , h - j , n and p )

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other glucose-lowering drugs in type 2 diabetes: a systematic review and meta-analysis of real-world studies

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