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Their effect is more general through the receptors for advanced glycation end products (RAGE), which are concentrated in the heart, lungs, and skeletal muscles

Consent for publication All participants included in this study provided written informed consent

It can be sensed by cyclic GMP-AMP synthase (cGAS), activating the stimulator of interferon genes (STING) pathway

Furthermore, they were N-terminally tagged with an SV40 nuclear localization sequence, with a HaloTag (Promega) and with eGFP to obtain pcDNA5-NLS-Halo-eGFP-BASU and pcDNA5-NLS-Halo-eGFP-BioID constructs, respectively