These include: Paraesthesia (pins and needles) in hands and feet Peripheral neuropathy with numbness or altered sensation Difficulty walking or balance problems (ataxia) Memory problems and cognitive difficulties Mood changes, including depression or irritability In severe cases, confusion or dementia-like symptoms Other manifestations may include: Loss of appetite and unintentional weight loss Constipation Visual disturbances (rare, but can occur with optic neuropathy) Important: The neurological complications of B12 deficiency can progress even in the absence of anaemia, making early detection crucial
Monitoring and Medical Supervision: While AOD-9604 has a favorable safety profile, medical supervision is recommended, particularly for individuals with pre-existing health conditions
Fatigue : While B12 typically boosts energy, some people might initially experience fatigue as their body adjusts to the treatment
As well, an underlying assumption of this analysis is that patients will comply with oral supplementation
Injections enter the body more directly
Clinical response rates in clinical trials have ranged from 30 to 60% over the first eight to 12 weeks, with endoscopic remission usually slower in onset
