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A 'metastasis-prone' signature for early-stage mismatch-repair proficient sporadic colorectal cancer patients and its implications for possible therapeutics

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10.1038/mp.2014.127 37 CissM.HalabiskyB.HarrisJ.DevidzeN.DubalD

2.4.3 Signaling pathway alterations Beyond activating inflammatory and cell death cascades, overwhelming oxidative stress pathologically alters numerous other intracellular signaling pathways crucial for myocardial function and survival