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doi: 10.1007/s00253-012-4442-0, PMID: [DOI] [PubMed] [Google Scholar] 65

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Seek medical advice if you experience : Severe or worsening symptoms : If leg discomfort becomes increasingly intense, frequent, or significantly disrupts your sleep and daily activities

Bacterial filamentation can be elicited by a variety of stressors including DNA damage, whereby the widely conserved stress response protein RecA inhibits cell division, causing bacteria to filament into long chains with a shared cytosol 31