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Both the ADA and the World Health Organization (WHO) have adopted fasting blood glucose (FBG), 2-hour postprandial blood glucose (2-h PG), and random blood glucose levels as diagnostic criteria for diabetes mellitus

Tirzepatide carries a boxed warning for risk of thyroid C-cell tumors and is contraindicated in patients with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2