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Effect of GH-RH antagonists on BPH The influence of GH-RH antagonists on animal models of BPH had not been investigated hence, we evaluated the effects of the GH-RH antagonist JMR-132 given at doses of 40 g/day, MIA-313 at 20 g/day, and MIA-459 at 20 g/day in testosterone-induced BPH in Wistar rats 46