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Evaluation of Tregs in vitro highlighted that CD25 expression was upregulated in luteolin-treated anti-CD3/CD28-activated CD4+CD25- T cells, characterized by upregulated IL-2, IL-10, and TGF-1 mRNA expression and downregulated IL-4 and IL-13 mRNA levels [159]

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Microsatellite instability is associated with the presence of lynch syndrome pan-cancer