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SELENOS is involved in the cellular response to ER stress (ER-associated degradation

Nymark, K.A

Some researchers have argued that when this protective layer is compromised, the brain may become vulnerable to damage from chemicals, inflammatory cytokines, and immune cells

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While it is possible that metabolite levels were affected by antipsychotic medication, our sample is comprised of the least-treated subjects of all MRS glutamate and GSH studies in schizophrenia reported to date (median treatment duration = 2.27 DDD-days)

On the molecular level, fisetin acts on multiple signaling pathways, including BCL-2, PI3K/AKT, p53, and NF- B, all of which are critical for senescence