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monitor thyroid function periodically Hypersensitivity reactions: May occur at injection site or systemically Concomitant medications: Drugs that suppress growth hormone release (such as glucocorticoids) may reduce sermorelins effectiveness Use under medical supervision: Growth hormone axis should be monitored by a qualified provider Common Side Effects Injection site reactions: pain, swelling, redness Flushing of the face Headache Dizziness Altered sense of taste Hyperactivity, restlessness, or insomnia Drowsiness or unusual tiredness Nausea, vomiting, or stomach pain Skin pallor at injection site Seek Medical Attention For Signs of allergic reaction: rash, hives, difficulty breathing, swelling Persistent severe headache Chest pain or irregular heartbeat Signs of hypothyroidism: extreme fatigue, cold intolerance, weight gain Drug Interactions Inform your provider of all medications, especially glucocorticoids, cyclooxygenase inhibitors, insulin, thyroid hormones, and any medications affecting growth hormone levels

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"Emerging Use of BPC-157 in Orthopaedic Sports Medicine: A Systematic Review." American Journal of Sports Medicine , 2025

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