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Dermatologists also call this lesion a labial lentigo or lip melanosis

Yunnan Key Laboratory of Integrated Traditional Chinese and Western Medicine for Chronic Disease in Prevention and Treatment (CWCD2023-002

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These hormones can stimulate melanocytes, leading to increased melanin production

doi: 10.3389/fmicb.2025.1606437 Received 07 April 2025 Accepted 30 May 2025 Published 25 June 2025 Corrected 26 June 2025 Volume 16 - 2025 Edited by Shyam Sundar Paul, ICAR, India Reviewed by Feed Research Institute (CAAS), Chinese Academy of Agricultural Sciences, China Wenchao Cai, Shihezi University, China Yafei Duan, South China Sea Fisheries Research Institute, China Muhammad Zahid Farooq, University of Veterinary and Animal Sciences, Pakistan Updates Copyright 2025 Liu, Li, Fan, Wang, Liu, Zhao and Yang

The clinical data anchors the biology