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Nineteen patients were treated with 20% honey solution eye drops three times a day 17 patients were treated with artificial tears three times a day as a control

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10.1161/01.cir.97.19.1930 Circulation

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Mechanistic studies have revealed that altered expression of iron metabolism-related proteins (including GPX4, FTH1, TfR1, and HO-1), accumulation of lipid peroxidation products, and disruption of antioxidant defense systems (particularly the Nrf2/GPX4 pathway) are central to ferroptosis progression in cardiac tissue