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Lipase inhibiting compounds other than Xenical have been developed, and polymers that bind fat to prevent its absorption have also been reported (3)

Sources: Dimet-Wiley AL, Latham CM, Brightwell CR, et al

Laboratory studies have also shown that GLP-1 receptor activation can reduce reward-seeking behaviors in models exposed to drugs or highly palatable foods, supporting the biological plausibility of these observations (2 Trusted Source The glucagon-like peptide-1 analogue exendin-4 decreases the rewarding value of food and drug rewards

Other labeled risks: intestinal obstruction