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2,3 In laboratory studies, MC4R knockout rats have shown increased food intake, weight gain, and fat accumulation

(Source 1) Reason #3 - Better Energy and Mitochondrial Function NAD+ is a cofactor in the metabolic pathways that turn food into energy inside the mitochondria of cells

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Mounjaro (tirzepatide) is not approved by the FDA just for weight loss

This is particularly due to its association in the increased incidence of endometrial lesions (including hyperplasia, carcinomas, and sarcoma) found in women undergoing chronic treatment with tamoxifen