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Moreover, melatonin treatment can change the level of Bcl-2 in a way that facilitates the induction of apoptosis [165]

Abbreviations ASCA anti- Saccharomyces cerevisiae antibody FGID functional gastrointestinal disorders GF germ-free IEB intestinal epithelial barrier IBD inflammatory bowel disease IBS irritable bowel syndrome IBS-C constipation-predominant irritable bowel syndrome IBS-D diarrhea-predominant irritable bowel syndrome IBS-M irritable bowel syndrome with mixed bowel habit LPS lipopolysaccharides SCFA short-chain fatty acids

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10.18176/jiaci.0310 36 BindlishA.SawalA

How to Read This Safety Picture The documented AHK-Cu safety profile is narrow and reassuring as far as it goes: local skin reactions that are usually mild, an uncommon copper contact allergy in a sensitized minority, and the procedural risks of microneedling where it's added

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