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All primer pairs gave a single PCR product with a single peak in the dissociation curve

Adverse Events An adverse event (AE) is any untoward medical event that occurs in a subject receiving a pharmaceutical product: it does not necessarily have a causal relationship to the treatment Quick Reference Guide AE OR NOT AE?(That is the question) Patient goes to dentist for a scheduled cleaning NO Patient goes to dentist for toothache, has root canal procedure YES (Toothache is the AE, Root Canal is the treatment recorded on the con meds page) Patient goes to gynecologist for scheduled annual exam, is prescribed HRT as a prophylactic NO (but it is a change in con meds) Patient has a cosmetic procedure scheduled before start of study NO (but record treatment as a con med) Patient has a cosmetic procedure scheduled after start of study that is performed during the study NO (but record treatment as a con med) Adverse Event Recording If a procedure is planned and scheduled before a patient enters a clinical trial then that procedure and associated underlying condition are not considered as (S)AEs

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